Genomic analysis of ICE <i>Vch</i> Ban8: An atypical genetic element in <i>Vibrio cholerae</i>
| Title | Genomic analysis of ICE Vch Ban8: An atypical genetic element in Vibrio cholerae |
| Publication Type | Journal Articles |
| Year of Publication | 2012 |
| Authors | Taviani E, Spagnoletti M, Ceccarelli D, Haley BJ, Hasan NA, Chen A, Colombo MM, Huq A, Colwell RR |
| Journal | FEBS Letters |
| Issue | 11 |
| Pagination | 1617 - 1621 |
| Date Published | Apr-06-2012 |
| Abstract | Genomic islands (GIs) and integrative conjugative elements (ICEs) are major players in bacterial evolution since they encode genes involved in adaptive functions of medical or environmental importance. Here we performed the genomic analysis of ICEVchBan8, an unusual ICE found in the genome of a clinical non‐toxigenic Vibrio cholerae O37 isolate. ICEVchBan8 shares most of its genetic structure with SXT/R391 ICEs. However, this ICE codes for a different integration/excision module is located at a different insertion site, and part of its genetic cargo shows homology to other pathogenicity islands of V. cholerae. |
| URL | http://doi.wiley.com/10.1016/j.febslet.2012.03.064 |
| DOI | 10.1016/j.febslet.2012.03.064 |