Schistosoma mansoni genome: Closing in on a final gene set

TitleSchistosoma mansoni genome: Closing in on a final gene set
Publication TypeJournal Articles
Year of Publication2007
AuthorsHaas BJ, Berriman M, Hirai H, Cerqueira GG, LoVerde PT, El-Sayed NM
JournalExperimental Parasitology
Pagination225 - 228
Date Published2007/11//
ISBN Number0014-4894
KeywordsAnnotation, Gene finding, Genome, Schistosoma mansoni

The Schistosoma mansoni genome sequencing consortium has recently released the latest versions of the genome assembly as well as an automated preliminary gene structure annotation. The combined datasets constitute a vast resource for researchers to exploit in a variety of post-genomic studies with an emphasis of transcriptomic and proteomic tools. Here we present an innovative method used for combining diverse sources of evidence including ab initio gene predictions, protein and transcript sequence homologies, and cross-genome sequence homologies between S. mansoni and Schistosoma japonicum to define a comprehensive list of protein-coding genes.