Role of transposable elements in trypanosomatids

TitleRole of transposable elements in trypanosomatids
Publication TypeJournal Articles
Year of Publication2008
AuthorsBringaud F, Ghedin E, El-Sayed NM, Papadopoulou B
JournalMicrobes and Infection
Pagination575 - 581
Date Published2008/05//
ISBN Number1286-4579
KeywordsCellular function, Domestication, Evolution, Gene expression, Leishmania, Regulation of mRNA stability, Retroposon, Transposable element, Trypanosoma

Transposable elements constitute 2-5% of the genome content in trypanosomatid parasites. Some of them are involved in critical cellular functions, such as the regulation of gene expression in Leishmania spp. In this review, we highlight the remarkable role extinct transposable elements can play as the source of potential new functions.