@article {20372,
	title = {Environmental Factors Influencing Epidemic Cholera},
	journal = {The American Journal of Tropical Medicine and Hygiene},
	volume = {89},
	year = {2013},
	month = {Apr-09-2013},
	pages = {597 - 607},
	abstract = {Cholera outbreak following the earthquake of 2010 in Haiti has reaffirmed that the disease is a major public health threat. <em>Vibrio cholerae</em> is autochthonous to aquatic environment, hence, it cannot be eradicated but hydroclimatology-based prediction and prevention is an achievable goal. Using data from the 1800s, we describe uniqueness in seasonality and mechanism of occurrence of cholera in the epidemic regions of Asia and Latin America. Epidemic regions are located near regional rivers and are characterized by sporadic outbreaks, which are likely to be initiated during episodes of prevailing warm air temperature with low river flows, creating favorable environmental conditions for growth of cholera bacteria. Heavy rainfall, through inundation or breakdown of sanitary infrastructure, accelerates interaction between contaminated water and human activities, resulting in an epidemic. This causal mechanism is markedly different from endemic cholera where tidal intrusion of seawater carrying bacteria from estuary to inland regions, results in outbreaks.},
	issn = {0002-9637},
	doi = {10.4269/ajtmh.12-0721},
	url = {http://www.ajtmh.org/content/journals/10.4269/ajtmh.12-0721},
	author = {Huq, Anwar and Hasan, Nur and Akanda, Ali and Whitcombe, Elizabeth and Rita R Colwell and Haley, Bradd and Alam, Munir and Jutla, Antarpreet and Sack, R. Bradley}
}
