Deep-sea hydrothermal vent bacteria related to human pathogenic <i>Vibrio</i> species

TitleDeep-sea hydrothermal vent bacteria related to human pathogenic Vibrio species
Publication TypeJournal Articles
Year of Publication2015
AuthorsHasan NA, Grim CJ, Lipp EK, Rivera ING, Chun J, Haley BJ, Taviani E, Choi SYoung, Hoq M, A. Munk C, Brettin TS, Bruce D, Challacombe JF, J. Detter C, Han CS, Eisen JA, Huq A, Colwell RR
JournalProceedings of the National Academy of Sciences
PaginationE2813 - E2819
Date PublishedFeb-05-2017

Vibrio species are both ubiquitous and abundant in marine coastal waters, estuaries, ocean sediment, and aquaculture settings worldwide. We report here the isolation, characterization, and genome sequence of a novel Vibrio species, Vibrio antiquarius, isolated from a mesophilic bacterial community associated with hydrothermal vents located along the East Pacific Rise, near the southwest coast of Mexico. Genomic and phenotypic analysis revealed V. antiquarius is closely related to pathogenic Vibrio species, namely Vibrio alginolyticus, Vibrio parahaemolyticus, Vibrio harveyi, and Vibrio vulnificus, but sufficiently divergent to warrant a separate species status. The V. antiquarius genome encodes genes and operons with ecological functions relevant to the environment conditions of the deep sea and also harbors factors known to be involved in human disease caused by freshwater, coastal, and brackish water vibrios. The presence of virulence factors in this deep-sea Vibrio species suggests a far more fundamental role of these factors for their bacterial host. Comparative genomics revealed a variety of genomic events that may have provided an important driving force in V. antiquarius evolution, facilitating response to environmental conditions of the deep sea.

Short TitleProc Natl Acad Sci USA