@article {12950,
	title = {Effect of treatment on the dynamics of circulating hypodermin C in cattle naturally infested with Hypoderma lineatum (Diptera: Oestridae)},
	journal = {Veterinary Parasitology},
	volume = {113},
	year = {2003},
	month = {2003/05/01/},
	pages = {263 - 272},
	abstract = {An antigen capture ELISA, using a murine monoclonal antibody recognising recombinant hypodermin C (rHyC), was used to evaluate the influence of early treatment with eprinomectin (Eprinex{\textregistered}) or fenthion (Spotton{\textregistered}) on the kinetics of circulating hypodermin C in calves naturally infested with Hypoderma lineatum. No viable larvae were collected from treated animals, whereas a variable number of warbles were found in control animals. Treatment provoked a decrease in circulating HyC levels that was significant 9 days post-treatment (p.t.). Circulating antigen levels in the treated cattle remained detectable for approximately 99 days p.t. In contrast, control animals had no detectable antigen at 64 days p.t., 42 days earlier than in the treated animals. These results suggest that larvae were either gradually killed, resulting in slow release of antigen or they were encapsulated, leading to the slow liberation of antigen. Kinetics of circulating HyC did not differ among the two insecticide treatments. Antibodies persisted, in all groups, throughout the 120-day study. These results suggest that the antigen capture ELISA will be useful as a technique for detecting successful treatment of cattle grub infestations and for the detection of new infestations in previously infested cattle.},
	keywords = {Capture ELISA, Cattle-arthropoda, Control methods-arthropoda, Eprinomectin, Fenthion, Hypoderma spp.},
	isbn = {0304-4017},
	doi = {10.1016/S0304-4017(03)00084-0},
	url = {http://www.sciencedirect.com/science/article/pii/S0304401703000840},
	author = {Douglas D Colwell and Panadero-Fontan,Rosario and L{\'o}pez-Sandez,Ceferino and Parra-Fernandez,Francisco and Paz-Silva,A and S{\'a}nchez-Andrade,Rita and D{\i}́ez-Ba{\~n}os,Pablo}
}
